This is in Madison County NC.
Clintwood Garments on Factory Drive in Clintwood VA. I found a couple of references to women who had worked here for 30 years or so. One lady was noted to have worked here in the 1970s and retired with brown lung. This company made undergarments, generally. I don’t know when it closed.
This is the Mason-Dorton School in Russell County VA, on 606 between Nickelsville and Dickensonville. It was built in 1885 and closed in 1958. It’s on the National Register of Historic Places. The plaque is on the other side, which only has a door, no windows.